The doctor is in! Doctor Mario (otherwise referred as Future Mario) is Mario who.. well, came from the future after a hard loss (Say, where's his brother?) and whilst our Mario's doing everything as normal, this Mario took it as a sign to finally rest. And by finally rest, I mean get a doctor's degree.
His best cure are the pills he uses to erradicate viruses from within. He's not completely out of the danger zone, though. Bigger viruses attack him on his off days, and he gets caught up in trouble other times. In very rare cases, he has to join forces with Mario to stop a bigger threat.
Regardless of any change, he's still Mario at the end of the day.
FUN FACTS
Whilst Dr. Mario & Mario aren't the same person, up until the Otherworld attacked, they lived the same life.
Due to the Otherworld's attacks, One of Dr. Mario's hands have been reduced to mere bones. With the right power, magic and will, it still functions! It even helps during the doctor job occasionally.
Whilst there's a Dr. Mario, unless the current Luigi takes the job, there isn't a Dr. Luigi. Dr. Mario's Luigi isn't around anymore.
Dr. Mario still finds the new life quite odd, but loves being around helping out.